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The influence of contrast media on kidney function in patients with stable coronary artery disease.
- Source :
- Scandinavian Cardiovascular Journal; Aug2014, Vol. 48 Issue 4, p234-240, 7p
- Publication Year :
- 2014
-
Abstract
- Aims. To investigate the incidence of contrast media-induced nephropathy (CIN) in patients with stable coronary artery disease (CAD) referred for elective coronary intervention following hydration routines. The reversibility of CIN was followed in a 6 month-period. Methods and results. A total of 447 patients referred for elective coronary intervention due to suspected CAD were included. Blood samples were collected before and 24 h after intervention and medical records were obtained. Patients had no drinking fluid restrictions and were routinely treated with a 1000 ml saline infusion. All patients were invited to a 6-month examination and collection of blood samples. Results. A total of 19 patients (4.3%) developed CIN. CIN patients had a pre-investigation higher estimated glomerular filtration rate (eGRF), lower level of kidney failure and lower creatinine level than non-CIN patients. Kidney function was not normalized in CIN patients 6 months after the intervention. Two patients still met the definition of CIN. Conclusion. With no restriction in fluid intake and supplementary infusion of saline, only a few patients with stable CAD developed early indications of CIN during elective coronary interventions. Kidney function and the amount of contrast media used was not a predictor of CIN development. The induced CIN was not completely normalized in a 6-month follow-up period. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14017431
- Volume :
- 48
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Scandinavian Cardiovascular Journal
- Publication Type :
- Academic Journal
- Accession number :
- 97113151
- Full Text :
- https://doi.org/10.3109/14017431.2014.934713