Back to Search
Start Over
Milk and Dairy Consumption and Risk of Dementia in an Elderly Japanese Population: The Hisayama Study.
- Source :
- Journal of the American Geriatrics Society; Jul2014, Vol. 62 Issue 7, p1224-1230, 7p, 1 Chart, 1 Graph
- Publication Year :
- 2014
-
Abstract
- Objectives To determine the effect of milk and dairy intake on the development of all-cause dementia and its subtypes in an elderly Japanese population. Design Prospective cohort study. Setting The Hisayama Study, Japan. Participants Individuals aged 60 and older without dementia (N = 1,081). Measurements Milk and dairy intake was estimated using a 70-item semiquantitative food frequency questionnaire grouped into quartiles. The risk estimates of milk and dairy intake on the development of all-cause dementia, Alzheimer's disease ( AD), and vascular dementia (VaD) were computed using a Cox proportional hazards model. Results Over 17 years of follow-up, 303 subjects developed all-cause dementia; 166 had AD, and 98 had VaD. The age- and sex-adjusted incidence of all-cause dementia, AD, and VaD significantly decreased as milk and dairy intake level increased ( P for trend = .03 for all-cause dementia, .04 for AD, .01 for VaD). After adjusting for potential confounders, the linear relationship between milk and dairy intake and development of AD remained significant ( P for trend = .03), whereas the relationships with all-cause dementia and VaD were not significant. The risk of AD was significantly lower in the second, third, and fourth quartiles of milk and dairy intake than in the first quartile. Conclusion Greater milk and dairy intake reduced the risk of dementia, especially AD, in the general Japanese population. [ABSTRACT FROM AUTHOR]
- Subjects :
- ALZHEIMER'S disease risk factors
DEMENTIA risk factors
VASCULAR dementia
CONFIDENCE intervals
DAIRY products
JAPANESE people
MILK
NUTRITIONAL assessment
REGRESSION analysis
RESEARCH funding
SURVIVAL analysis (Biometry)
LOGISTIC regression analysis
PROPORTIONAL hazards models
DATA analysis software
DESCRIPTIVE statistics
OLD age
DISEASE risk factors
Subjects
Details
- Language :
- English
- ISSN :
- 00028614
- Volume :
- 62
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Journal of the American Geriatrics Society
- Publication Type :
- Academic Journal
- Accession number :
- 97053056
- Full Text :
- https://doi.org/10.1111/jgs.12887