Genetic variants in the P2 RX7 gene are associated with risk of multiple myeloma.

Authors :: Vangsted, Annette J.
Klausen, Tobias W.
Gimsing, Peter
Abildgaard, Niels
Andersen, Niels F.
Gang, Anne O.
Holmström, Morten
Gregersen, Henrik
Vogel, Ulla
Schwarz, Peter
Jørgensen, Niklas R.
Source :: European Journal of Haematology; Aug2014, Vol. 93 Issue 2, p172-174, 3p
Publication Year :: 2014
Abstract: The article presents a population-based study of 348 myeloma patients undergoing autologous transplant. The researchers have tested functionally important polymorphisms in the P2RX7 and P2RY2 genes for association with risk of disease. Chi-square test or fisher's exact test, Kaplan-Meier method and log rank test, and cox proportional hazard analysis were used in the study.

Subjects :: MULTIPLE myeloma
AUTOGRAFTS
GENETIC polymorphisms
CHI-squared test
KAPLAN-Meier estimator
PROPORTIONAL hazards models
PATIENTS

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