Back to Search Start Over

Supercooling enables long-term transplantation survival following 4 days of liver preservation.

Authors :
Berendsen, Tim A
Bruinsma, Bote G
Puts, Catheleyne F
Saeidi, Nima
Usta, O Berk
Uygun, Basak E
Izamis, Maria-Louisa
Toner, Mehmet
Yarmush, Martin L
Uygun, Korkut
Source :
Nature Medicine; Jul2014, Vol. 20 Issue 7, p790-793, 4p
Publication Year :
2014

Abstract

The realization of long-term human organ preservation will have groundbreaking effects on the current practice of transplantation. Herein we present a new technique based on subzero nonfreezing preservation and extracorporeal machine perfusion that allows transplantation of rat livers preserved for up to four days, thereby tripling the viable preservation duration. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10788956
Volume :
20
Issue :
7
Database :
Complementary Index
Journal :
Nature Medicine
Publication Type :
Academic Journal
Accession number :
96939660
Full Text :
https://doi.org/10.1038/nm.3588