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Patch Testing with Formaldehyde 2.0% in Parallel with 1.0% by the Swedish Contact Dermatitis Research Group.
- Source :
- Acta Dermato-Venereologica; Jul2014, Vol. 94 Issue 4, p408-410, 3p, 1 Chart
- Publication Year :
- 2014
-
Abstract
- In a multicentre study consecutively patch-tested dermatitis patients were tested simultaneously with 1.0% and 2.0% (w/v) formaldehyde in aqua applied with a micropipette (15 μl) to the filter paper disc in Finn Chambers (0.30 mg/cm<superscript>2</superscript> and 0.60 mg/cm<superscript>2</superscript>, respectively). A total of 2,122 dermatitis patients were patch-tested. In all, 77 (3.6%) patients reacted positively to formaldehyde; 37 reacted only to 2.0%, 35 reacted to both concentrations and 5 patients reacted only to 1.0%. Significantly more patients were thus diagnosed with contact allergy to formaldehyde with 2.0% compared to 1.0% (p < 0.001) without causing more irritant reactions. The detected number of isolated allergic reactions to the 2 formaldehyde- releasers in the Swedish baseline series and not to formaldehyde itself raises the question whether quaternium-15 1.0% and diazolidinyl urea 2.0% should be present in the Swedish baseline series. [ABSTRACT FROM AUTHOR]
- Subjects :
- CONTACT dermatitis
SKIN tests
SKIN inflammation
FORMALDEHYDE
ALLERGENS
Subjects
Details
- Language :
- English
- ISSN :
- 00015555
- Volume :
- 94
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Acta Dermato-Venereologica
- Publication Type :
- Academic Journal
- Accession number :
- 96764778
- Full Text :
- https://doi.org/10.2340/00015555-1748