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On the origin of sustained negative BOLD response.
- Source :
- Journal of Neurophysiology; Nov2012 part1, Vol. 108 Issue 9, p2339-2342, 4p
- Publication Year :
- 2012
-
Abstract
- Several brain regions exhibit a sustained negative BOLD response (NBR) during specific tasks, as assessed with functional magnetic resonance imaging. The origin of the NBR and the relationships between the vascular/metabolic dynamics and the underlying neural activity are highly debated. Converging evidence indicates that NBR, in human and non-human primates, can be interpreted in terms of decrease in neuronal activity under its basal level, rather than a purely vascular phenomenon. However, the scarcity of direct experimental evidence suggests caution and encourages the ongoing utilization of multimodal approaches in the investigation of this effect. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00223077
- Volume :
- 108
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- Journal of Neurophysiology
- Publication Type :
- Academic Journal
- Accession number :
- 96265751
- Full Text :
- https://doi.org/10.1152/jn.01199.2011