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A77: Clinical and Laboratory Features and Systemic Lupus Erythematous Disease Activity Index 2000 (SLEDAI 2K) at Onset and Follow Up in a Cohort of 109 Paediatric Lupus Patients From a Tertiary Level Centre in India.
- Source :
- Arthritis & Rheumatology; Mar2014 Supplement, Vol. 66, pS109-S110, 2p
- Publication Year :
- 2014
-
Abstract
- Background/Purpose: Pediatric Rheumatology is a relatively new branch in India. To the best of our knowledge, this is the first paper that has studied SLEDAI 2K in 109 children with SLE at onset, 6 months and annually thereafter for a median follow up of 38 months. Methods: In our unit, disease activity of all children with lupus is captured on disease assessment proformas and completed every 3-6 months. This form captures demographics, clinical assessment, lab results and therapy. All paediatric lupus patients (diagnosed per the ACR criteria 1992) with disease onset <18 years seen at our unit from 2001 were included. The clinical and laboratory features at presentation and the SLEDAI 2K was captured at onset, 6 months and thereafter annually. We chose SLE 2K as an outcome measure as it captures new, recurrent and ongoing disease activity (). The aims of the study were To detail the presentation of cSLE from India, To study the SLEDAI 2K at onset and follow up, To compare the data from India to that available from the West., available from the West. Results: Demographics: 109 patients identified, 90 were females. The median age at onset was 11.4 (3.4-18) years and median age at diagnosis 12.1 (3.5-19). The median duration of follow up was 38 months (3-152). Clinical presentation at onset: As in table . Nine children had MAS at onset. [ABSTRACT FROM AUTHOR]
- Subjects :
- SYSTEMIC lupus erythematosus diagnosis
QUESTIONNAIRES
DESCRIPTIVE statistics
Subjects
Details
- Language :
- English
- ISSN :
- 23265191
- Volume :
- 66
- Database :
- Complementary Index
- Journal :
- Arthritis & Rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 95124803
- Full Text :
- https://doi.org/10.1002/art.38493