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Individual and partner risk factors associated with abnormal cervical cytology among women in HIV-discordant relationships.
- Source :
- International Journal of STD & AIDS; Apr2014, Vol. 25 Issue 5, p315-324, 10p, 6 Charts
- Publication Year :
- 2014
-
Abstract
- Individual and sexual partner characteristics may increase the risk of abnormal cervical cytology among women in human immunodeficiency virus (HIV)-discordant relationships. Papanicolaou smears were obtained in a prospective cohort of Kenyan HIV-discordant couples. Of 441 women, 283 (64%) were HIV-infected and 158 (36%) were HIV-uninfected with HIV-infected partners. Overall, 79 (18%) had low-grade and 25 (6%) high-grade cervical abnormalities. Male herpes simplex virus type 2 (HSV-2) seropositivity and lower couple socioeconomic status were associated with cervical abnormalities (p < 0.05). HIV-uninfected women with HIV-infected male sex partners (CD4 > 350 cells/µL) had the lowest prevalence of high-grade cervical lesions. HIV-infected women (CD4 > 350 cells/µL) and HIV-uninfected women with HIV-infected partners (CD4 ≤ 350 cells/µL) were at similar intermediate risk (p > 0.05), and HIV-infected women (CD4 ≤ 350 cells/µL) had significantly higher risk of high-grade cervical abnormalities (p = 0.05). Women in HIV-discordant relationships have high rates of cervical lesions and this may be influenced by couple-level factors, including HIV status and CD4 count of the infected partner. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09564624
- Volume :
- 25
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- International Journal of STD & AIDS
- Publication Type :
- Academic Journal
- Accession number :
- 95097430
- Full Text :
- https://doi.org/10.1177/0956462413504554