Fatigue in Ménière's disease.

Objective: To explore the role of fatigue and its predisposing and consequential factors and consequences, on quality of life and social participation. Subjects and methods: A questionnaire survey of 728 members of the Finnish Ménière Association was performed. Questions focused on the symptoms of Ménière's disease, sense of coherence (SOC), positive attitude, participation and restriction problems classified by the International Classification of Function (ICF), and general health related quality of life (EQ-5D). Results: Seventy percent of the subjects reported fatigue and in 30% fatigue was moderate or strong. Fatigue was associated with reduced quality of life and complaints of vertigo attacks, balance problems and hearing loss. Mobility related symptoms and mood disorders in a broad sense were the most significant determinants of fatigue. SOC and attitude were predictors of reduced vitality. Analysis based on participation restrictions indicated isolation being a consequence of fatigue. In the analysis the severity of the disease was controlled. Conclusion: Fatigue is a common complaint in Ménière's disease, reducing quality of life and leading to social and personal isolation. Fatigue is associated with personality trait and anxiety disorders. Therapeutically, a positive attitude and physical activity might help to reduce anxiety and escape the social and personal isolation. [ABSTRACT FROM AUTHOR]