One sided axillary lymphadenopathy as the only manifestation of single-center Castleman disease.

Castleman's disease is characterized by lymphadenopathy, with or without systematic symptoms .It comprises of two distinct types, monocentric type which is a benign lymphoproliferative disease, and multicentric type, which is associated with human immunodeficiency virus (HIV) infection . A 36 year old man was attended due to palpation of a sizable, painless mass in the right axilla. He had a previous history of intravenous drug addiction. His medical history, also revealed repeated scratches from his cat. Moreover, his clinical examination revealed the presence of a swollen lymph node group in the right axilla and multiple lacerations in the upper extremities. No other palpable lymph node groups were detected. The serological tests for HIV and Bartonella were negative. A resection of the lymphatic block was performed and the biopsy culture was negative. However, biopsy revealed monocentric Castleman disease, hyaline - vascular type, which is a rare manifestation of the disease since it usually presents as mediastinal, hilar or intraabdominal lymphadenopathy, and rarely as a single peripheral. The resection of the lymphatic block was sufficient to cure the patient. The monocentric Castleman disease is a rare but possible cause of peripheral lymphadenopathy . [ABSTRACT FROM AUTHOR]