Electrochemical Attributes of Electrochemistry in Tandem with Electrospray Mass Spectrometry.

Electrolytic efficiency of battery-operated flow-through thin-layer electrochemical (EC; echem) cell used in EC/ESI-MS was investigated. Two stainless steel capillaries joined by PTFE tubing formed the thin-layer EC cell. Echem reaction efficiency of ferrocyanide, dopamine and hydroquinone oxidation in the EC cell was low and decreased with increasing MeOH volume fraction in the MeOH/H₂O carrier solutions with low conductivity. Water oxidation dominated the cell current and migration of ferrocyanide was observed. Flow rate of 50-200 µL/h had a very small effect on EC cell current. Dopamine oxidation current in the EC cell and dopamine ion intensity in EC/ESI-MS showed a direct correlation. [ABSTRACT FROM AUTHOR]