Quality-of-life scores compared to objective measures of swallowing after oropharyngeal chemoradiation.

Objectives/Hypothesis To compare objective measures of swallowing function with patient reports of swallowing-related quality of life 1 year after treatment of oropharyngeal cancer with chemoradiation therapy. Study Design Patients seen for follow-up at least 1 year after treatment of oropharyngeal carcinoma with chemoradiation therapy were sequentially approached and asked to participate in the study. Methods Maximum pharyngeal constriction, hyoid elevation, upper esophageal sphincter opening size, and bolus pharyngeal transit time were measured from modified barium swallowing studies in a group of 31 patients at least 1 year after chemoradiation therapy for the treatment of oropharyngeal carcinoma. Measures were made for a liquid 1-mL, 3-mL, and 20-mL bolus. Objective measure results were compared to scores from the MD Anderson Dysphagia Inventory and The University of Washington Swallowing Quality of Life Questionnaire results from the same patients. Results No strong correlation was identified between any of the objective measures of swallowing physiology and quality-of-life scores. Conclusions Patient perception of the impact of swallowing function on quality of life does not correlate well with actual physiologic functioning. Level of Evidence 4. Laryngoscope, 124:682-687, 2014 [ABSTRACT FROM AUTHOR]