Plasma ≈-carotene and retinol concentrations of children increase after a 30-d supplementation with the fruit Momordica cochinchinensis (gac).

Background: In rural Vietnam, vitamin A deficiency is a concern. Among the indigenous fruit and vegetables, Momordica cochinchinensis (gac) fruit has been identified as having the highest β-carotene concentration. Locally, it is mixed with rice in a preparation called xoi gac. Objective: The purpose of this study was to assess this β-carotene- rich rice preparation as a source of provitamin A for children in rural Vietnam. Design: Preschoolers (n = 185) participated in a 30-d controlled supplementation trial. Children with low hemoglobin concentrations were assigned to 1 of 3 groups: a fruit group, who received xoi gac that contained 3.5 mg β-carotene per serving; a powder group, who received rice mixed with 5.0 mg synthetic β-carotene powder; and a control group, who received rice without fortification. Results: The mean increase in plasma β-carotene concentrations in the fruit and powder groups was significantly greater than that in the control group (P < 0.0001). After supplementation, the mean plasma retinol concentration in the fruit group was significantly higher than that in the control (P = 0.006) and powder (P = 0.0053) groups. Among the children with initial hemoglobin concentrations ⩽ 110 g/L, the mean increase in hemoglobin concentrations in the fruit group was marginally higher than that in the control group (P = 0.017) but was not significantly different from that in the powder group. Conclusions: β-Carotene from xoi gac is a good source of provitamin A carotenoids. Severely anemic children might particularly benefit from routine xoi gac consumption. [ABSTRACT FROM AUTHOR]