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Key outcomes are usually not reported in published fracture secondary prevention programs: results of a systematic review.
- Source :
- Archives of Orthopaedic & Trauma Surgery; Feb2014, Vol. 134 Issue 2, p283-289, 7p, 3 Charts
- Publication Year :
- 2014
-
Abstract
- Objective: A secondary analysis of a systematic review on interventions to improve osteoporosis (OP) investigation and treatment was conducted to examine reported key outcomes: (1) the cost of the intervention; (2) the proportion of patients taking OP medication beyond 6 months of the intervention; and (3) the proportion of patients who re-fractured. Methods: Fifty-seven articles reporting on 54 studies (64 interventions) from 11 countries were included. Intervention studies to improve OP management were eligible if they were conducted in an orthopedic setting and included primary data on ≥20 patients presenting with a hip fracture or any fragility fracture. To compare outcome data across all interventions regardless of study design, an equated proportion (EP) using a denominator based on the intention-to-treat principle was derived. Whether a cost analysis had been conducted, the EP of patients who were taking medication beyond 6 months of the intervention, and the EP of patients who re-fractured during the study period were documented. Results: Of the 54 studies, 2 reported a cost analysis and demonstrated that the interventions were at least cost-effective. The EP for medication use beyond 6 months of the intervention ranged from 17 to 56% for four studies. The EP for re-fracture ranged from 0 to 5% for four studies. Conclusion: Most interventions did not report key outcomes. In addition, authors used varying time frames for re-fracture and medication use, making direct comparisons impossible. Authors should consider including intervention costs, medication use beyond 6 months of the intervention, and re-fracture data in future fracture secondary prevention programs. [ABSTRACT FROM AUTHOR]
- Subjects :
- BONE fractures
OSTEOPOROSIS
MEDICATION errors
COST analysis
COST effectiveness
Subjects
Details
- Language :
- English
- ISSN :
- 09368051
- Volume :
- 134
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Archives of Orthopaedic & Trauma Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 94081662
- Full Text :
- https://doi.org/10.1007/s00402-011-1442-y