Back to Search
Start Over
Secondary primary cancer in patients with head and neck carcinoma: the differences among hypopharyngeal, laryngeal, and other sites of head and neck cancer.
- Source :
- European Journal of Cancer Care; Jan2014, Vol. 23 Issue 1, p36-42, 7p, 3 Charts
- Publication Year :
- 2014
-
Abstract
- This paper presents a population-based retrospective cohort study to identify the differences in secondary primary cancer ( SPC) among hypopharyngeal, laryngeal, and other sites of head and neck cancer ( HNC). Data were collected from the Taiwan National Health Insurance Research Database ( NHIRD) for the period 1979-2010. The study cohort comprised 5914 newly diagnosed hypopharyngeal and laryngeal patients from the registry of the Catastrophic Illness Patients Database ( CIPD). The comparison cohort comprised 5914 patients with other sites of HNC. We used a multivariate Cox proportional-hazards regression model to assess the risk of developing SPC. The incidence of SPC in the study cohort was 68% higher compared with the comparison cohort (23.9 vs. 14.2 per 1000 person-years, Incident Rate Ratio = 1.68). The study cohort had a higher adjusted hazard ratio ( HR) in oesophageal cancer ( HR = 3.47) and lung cancer ( HR = 1.89). The difference in SPC incidence between the study and comparison cohort was significant. [ABSTRACT FROM AUTHOR]
- Subjects :
- ACADEMIC medical centers
CHI-squared test
CONFIDENCE intervals
DATABASES
HEAD tumors
MEDICAL information storage & retrieval systems
LARYNGEAL tumors
MULTIVARIATE analysis
NECK tumors
POISSON distribution
RESEARCH funding
HYPOPHARYNX
DISEASE incidence
PROPORTIONAL hazards models
DATA analysis software
DESCRIPTIVE statistics
SECONDARY primary cancer
TUMORS
Subjects
Details
- Language :
- English
- ISSN :
- 09615423
- Volume :
- 23
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- European Journal of Cancer Care
- Publication Type :
- Academic Journal
- Accession number :
- 93316395
- Full Text :
- https://doi.org/10.1111/ecc.12084