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The bacterial Sec-translocase: structure and mechanism.

Authors :
Lycklama a Nijeholt, Jelger A.
Driessen, Arnold J. M.
Source :
Philosophical Transactions of the Royal Society B: Biological Sciences; 4/19/2012, Vol. 367 Issue 1592, p1015-1028, 14p
Publication Year :
2012

Abstract

Most bacterial secretory proteins pass across the cytoplasmic membrane via the translocase, which consists of a protein-conducting channel SecYEG and an ATP-dependent motor protein SecA. The ancillary SecDF membrane protein complex promotes the final stages of translocation. Recent years have seen a major advance in our understanding of the structural and biochemical basis of protein translocation, and this has led to a detailed model of the translocation mechanism. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09628436
Volume :
367
Issue :
1592
Database :
Complementary Index
Journal :
Philosophical Transactions of the Royal Society B: Biological Sciences
Publication Type :
Academic Journal
Accession number :
92693397
Full Text :
https://doi.org/10.1098/rstb.2011.0201