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Palmitate increases Nur77 expression by modulating ZBP89 and Sp1 binding to the Nur77 proximal promoter in pancreatic β-cells.
- Source :
- FEBS Letters; Nov2013, Vol. 587 Issue 23, p3883-3890, 8p
- Publication Year :
- 2013
-
Abstract
- Highlights: [•] Nur77 promoter activity is regulated by palmitate in MIN6 cells. [•] Palmitate treatment modulates the balance between ZBP89 and Sp1 binding to the Nur77 promoter. [•] Activation of Nur77 promoter by palmitate is modulated by ZBP89 and Sp1. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00145793
- Volume :
- 587
- Issue :
- 23
- Database :
- Complementary Index
- Journal :
- FEBS Letters
- Publication Type :
- Academic Journal
- Accession number :
- 92502973
- Full Text :
- https://doi.org/10.1016/j.febslet.2013.10.024