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The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis.
- Source :
- Rheumatology; Dec2013, Vol. 52 Issue 12, p2136-2148, 13p, 1 Diagram, 5 Charts
- Publication Year :
- 2013
-
Abstract
- Objective. There is substantial uncertainty regarding the prevalence of depression in RA. We conducted a systematic review aiming to describe the prevalence of depression in RA.Methods. Web of Science, PsycINFO, CINAHL, Embase, Medline and PubMed were searched for cross-sectional studies reporting a prevalence estimate for depression in adult RA patients. Studies were reviewed in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines and a meta-analysis was performed.Results. A total of 72 studies, including 13 189 patients, were eligible for inclusion in the review. Forty-three methods of defining depression were reported. Meta-analyses revealed the prevalence of major depressive disorder to be 16.8% (95% CI 10%, 24%). According to the PHQ-9, the prevalence of depression was 38.8% (95% CI 34%, 43%), and prevalence levels according to the HADS with thresholds of 8 and 11 were 34.2% (95% CI 25%, 44%) and 14.8% (95% CI 12%, 18%), respectively. The main influence on depression prevalence was the mean age of the sample.Conclusion. Depression is highly prevalent in RA and associated with poorer RA outcomes. This suggests that optimal care of RA patients may include the detection and management of depression. [ABSTRACT FROM PUBLISHER]
- Subjects :
- DIAGNOSIS of mental depression
MENTAL depression risk factors
AGE distribution
CINAHL database
CONFIDENCE intervals
MEDICAL information storage & retrieval systems
PSYCHOLOGY information storage & retrieval systems
MEDLINE
META-analysis
ONLINE information services
HEALTH outcome assessment
RESEARCH funding
RHEUMATOID arthritis
STATISTICS
SYSTEMATIC reviews
DATA analysis
TREATMENT effectiveness
DISEASE prevalence
DATA analysis software
DESCRIPTIVE statistics
DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 14620324
- Volume :
- 52
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- Rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 92051422
- Full Text :
- https://doi.org/10.1093/rheumatology/ket169