Back to Search
Start Over
Chicago Healthy Aging Study: Objectives and Design.
- Source :
- American Journal of Epidemiology; Sep2013, Vol. 178 Issue 4, p635-644, 10p
- Publication Year :
- 2013
-
Abstract
- Investigators in the Chicago Healthy Aging Study (CHAS) reexamined 1,395 surviving participants aged 65–84 years (28% women) from the Chicago Heart Association Detection Project in Industry (CHA) 1967–1973 cohort whose cardiovascular disease (CVD) risk profiles were originally ascertained at ages 25–44 years. CHAS investigators reexamined 421 participants who were low-risk (LR) at baseline and 974 participants who were non-LR at baseline. LR was defined as having favorable levels of 4 major CVD risk factors: serum total cholesterol level <200 mg/dL and no use of cholesterol-lowering medication; blood pressure 120/≤80 mm Hg and no use of antihypertensive medication; no current smoking; and no history of diabetes or heart attack. While the potential of LR status in overcoming the CVD epidemic is being recognized, the long-term association of LR with objectively measured health in older age has not been examined. It is hypothesized that persons who were LR in 1967–1973 and have survived to older age will have less clinical and subclinical CVD, lower levels of inflammatory markers, and better physical performance/functioning and sleep quality. Here we describe the rationale, objectives, design, and implementation of this longitudinal epidemiologic study, compare baseline and follow-up characteristics of participants and nonparticipants, and highlight the feasibility of reexamining study participants after an extended period postbaseline with minimal interim contact. [ABSTRACT FROM AUTHOR]
- Subjects :
- HYPOTHESIS
AGING
BIOMARKERS
CARDIOVASCULAR diseases risk factors
ELECTROCARDIOGRAPHY
EXPERIMENTAL design
INTERVIEWING
LIFE skills
LONGITUDINAL method
NEUROPSYCHOLOGICAL tests
METROPOLITAN areas
PHYSICAL diagnosis
PSYCHOLOGICAL tests
QUESTIONNAIRES
MEDICAL digital radiography
RESEARCH funding
SLEEP
SECONDARY analysis
REPEATED measures design
STATE-Trait Anxiety Inventory
DESCRIPTIVE statistics
Subjects
Details
- Language :
- English
- ISSN :
- 00029262
- Volume :
- 178
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- American Journal of Epidemiology
- Publication Type :
- Academic Journal
- Accession number :
- 89734112
- Full Text :
- https://doi.org/10.1093/aje/kwt020