Unidirectional Scaffold-Strand Arrangement in DNA Origami.

In a parallel universe: DNA origami structures based on modified parallel double‐crossover tiles (see scheme) were constructed and a unidirectional (parallel) arrangement of the scaffold strand (gray lines) was used in the assembly of a variety of 2D and 3D DNA origami structures. This will greatly expand the diversity of DNA origami and enable their assembly into larger structures. [ABSTRACT FROM AUTHOR]