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Effect of bolus injection of 20 ml saline with arm elevation on the onset time of vecuronium administered via a peripheral vein: a randomised controlled trial.
- Source :
- Anaesthesia; Sep2013, Vol. 68 Issue 9, p904-907, 4p, 2 Charts
- Publication Year :
- 2013
-
Abstract
- We investigated whether a bolus injection of 20 ml saline with arm elevation might shorten the onset time of vecuronium administered via a dorsal hand vein. Thirty patients were randomly allocated to the bolus saline group or control group. General anaesthesia was induced and maintained with remifentanil and propofol. Vecuronium 0.1 mg.kg<superscript>−1</superscript> was administered to all patients, followed in the treatment group by bolus injection of 20 ml saline and arm elevation. Response to train-of-four stimulation was measured by acceleromyography at the adductor pollicis muscle. The mean (SD) lag time was 47.2 (14.5) s in the bolus saline group and 67.9 (12.2) s in the control group (p = 0.0002). The time to 95% block of T1 was 104.6 (29.9) s in the bolus saline group and 128.3 (15.8) s in the control group (p = 0.011). Bolus saline injection results in shortened lag time and onset time of neuromuscular block with vecuronium. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00032409
- Volume :
- 68
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- Anaesthesia
- Publication Type :
- Academic Journal
- Accession number :
- 89658637
- Full Text :
- https://doi.org/10.1111/anae.12333