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Omega-3 Fatty Acids for Prevention of Breast Cancer: an Update and the State of the Science.
- Source :
- Current Breast Cancer Reports; Sep2013, Vol. 5 Issue 3, p247-254, 8p
- Publication Year :
- 2013
-
Abstract
- The quantity and makeup of dietary fat intake are known to affect human health. A variety of purported health benefits, including cancer prevention, have focused increased attention on use of omega-3 (ω-3) polyunsaturated fatty acid (PUFA) supplements. Preclinical evidence has been encouraging, and recent studies have increased our understanding of mechanisms by means of which ω-3 PUFAs may protect against breast cancer. However, epidemiological studies have yielded mixed results. Recent population studies have attempted to determine factors, for example total fat intake and the ratio of ω-3 to ω-6 PUFA intake, that may affect the action of ω-3 PUFAs. Several clinical trials, some currently ongoing, are investigating strategies to favorably alter endogenous fatty acid profiles in an attempt to develop clinically feasible prevention methods. Identification of well-defined subpopulations who are most likely to benefit from a targeted prevention approach will probably be crucial to this effort. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 19434588
- Volume :
- 5
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Current Breast Cancer Reports
- Publication Type :
- Academic Journal
- Accession number :
- 89547662
- Full Text :
- https://doi.org/10.1007/s12609-013-0112-1