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Spontaneous regression of metastatic melanoma after inoculation with tetanus-diphtheria-pertussis vaccine.
- Source :
- Current Oncology; Jun2013, Vol. 20 Issue 3, pe270-e273, 4p, 1 Color Photograph
- Publication Year :
- 2013
-
Abstract
- Spontaneous regression of metastatic melanoma is an exceedingly rare event, with only 76 well-documented cases in the literature since 1866. Here, we present the case of a patient who developed metastatic melanoma despite interferon therapy and who then achieved spontaneous regression shortly after a reaction to tetanus-diphtheria-pertussis vaccination. A common theme among these cases is the development of febrile illness before remission of the malignant disease. A brief overview of proposed mechanisms for these miraculous recoveries is presented, including a highlight on the potential role of the HERV-K-MEL viral marker, a nona- or decapeptide that appears in most melanomas, with homologies to peptides in pathogenic microorganisms. [ABSTRACT FROM AUTHOR]
- Subjects :
- MELANOMA
TETANUS
DIPHTHERIA
WHOOPING cough
VACCINATION
Subjects
Details
- Language :
- English
- ISSN :
- 11980052
- Volume :
- 20
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Current Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 88157861
- Full Text :
- https://doi.org/10.3747/co.20.1212