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Moderate alcohol consumption predicts long-term mortality in elderly subjects with chronic heart failure.
- Source :
- Journal of Nutrition, Health & Aging; May2013, Vol. 17 Issue 5, p480-485, 6p
- Publication Year :
- 2013
-
Abstract
- Objective: Moderate alcohol consumption is related to a reduction of mortality. However, this phenomenon is not well established in the elderly, especially in the presence of chronic heart failure (CHF). The aim of the study was to verify the effect of moderate alcohol consumption on 12-year mortality in elderly community-dwelling with and without CHF. Settings: community-dwelling from 5 regions of Italy. Participants: A cohort of 1332 subjects aged 65 and older. Measurement: Mortality after 12-year follow-up in elderly subjects (≥65 years old) with and without CHF was studied. Moderate alcohol consumption was considered ≤250 ml/day (drinkers). Results: In the absence of CHF (n=947), mortality was 42.2% in drinkers vs. 53.7% in non-drinker elderly subjects (p=0.021). In contrast, in the presence of CHF (n=117), mortality was 86.5% in drinkers vs. 69.7% in non-drinker elderly subjects (p=0.004). Accordingly, Cox regression analysis shows that a moderate alcohol consumption is protective of mortality in the absence (HR=0.79; CI 95% 0.66-0.95; p<0.01) but it is predictive of mortality in the presence of CHF (HR=1.29; CI 95% 1.05-1.97; p<0.05). Conclusions: Our data demonstrates that moderate alcohol consumption is associated with an increased long-term mortality risk in the elderly in the presence of CHF. [ABSTRACT FROM AUTHOR]
- Subjects :
- ANALYSIS of variance
ANTHROPOMETRY
CHI-squared test
CONFIDENCE intervals
ALCOHOL drinking
HEART failure
MORTALITY
MULTIVARIATE analysis
STATISTICAL sampling
SURVIVAL analysis (Biometry)
COMORBIDITY
ACTIVITIES of daily living
CROSS-sectional method
PROPORTIONAL hazards models
GERIATRIC Depression Scale
DATA analysis software
DESCRIPTIVE statistics
OLD age
Subjects
Details
- Language :
- English
- ISSN :
- 12797707
- Volume :
- 17
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Journal of Nutrition, Health & Aging
- Publication Type :
- Academic Journal
- Accession number :
- 88059851
- Full Text :
- https://doi.org/10.1007/s12603-012-0430-4