Back to Search
Start Over
Impact of glycaemic index and dietary fibre on insulin sensitivity during the refeeding phase of a weight cycle in young healthy men.
- Source :
- British Journal of Nutrition; 5/14/2013, Vol. 109 Issue 9, p1606-1616, 11p
- Publication Year :
- 2013
-
Abstract
- Previous studies suggest that a low-glycaemic index (LGI) diet may improve insulin sensitivity (IS). As IS has been shown to decrease during refeeding, we hypothesised that an LGI- v. high-GI (HGI) diet might have favourable effects during this phase. In a controlled nutritional intervention study, sixteen healthy men (aged 26·8 (sd 4·1) years, BMI 23·0 (sd 1·7) kg/m2) followed 1 week of overfeeding, 3 weeks of energy restriction and of 2 weeks refeeding at ± 50 % energy requirement (50 % carbohydrates, 35 % fat and 15 % protein). During refeeding, subjects were divided into two matched groups receiving either high-fibre LGI or lower-fibre HGI foods (GI 40 v. 74, fibre intake 65 (sd 6) v. 27 (sd 4) g/d). Body weight was equally regained in both groups with refeeding (mean regain 70·5 (sd 28·0) % of loss). IS was improved by energy restriction and decreased with refeeding. The decreases in IS were greater in the HGI than in the LGI group (group × time interactions for insulin, homeostasis model assessment of insulin resistance (HOMAIR), Matsuda IS index (MatsudaISI); all P< 0·05). Mean interstitial glucose profiles during the day were also higher in the HGI group (ΔAUCHGI-LGI of continuous interstitial glucose monitoring: 6·6 mmol/l per 14 h, P= 0·04). At the end of refeeding, parameters of IS did not differ from baseline values in either diet group (adiponectin, insulin, HOMAIR, MatsudaISI, M-value; all P>0·05). In conclusion, nutritional stress imposed by dietary restriction and refeeding reveals a GI/fibre effect in healthy non-obese subjects. LGI foods rich in fibre may improve glucose metabolism during the vulnerable refeeding phase of a weight cycle. [ABSTRACT FROM PUBLISHER]
- Subjects :
- BLOOD sugar analysis
BODY composition
ANALYSIS of covariance
ANALYSIS of variance
ANTHROPOMETRY
CALORIMETRY
CLINICAL trials
DIET in disease
DIET therapy
DIETARY fiber
GLUCOSE tolerance tests
GLYCEMIC index
HOMEOSTASIS
INGESTION
INSULIN
INSULIN resistance
PLETHYSMOGRAPHY
PULMONARY gas exchange
RESEARCH funding
STATISTICAL sampling
STATISTICAL hypothesis testing
STATISTICS
T-test (Statistics)
DATA analysis
BODY mass index
RANDOMIZED controlled trials
DATA analysis software
ADIPONECTIN
DESCRIPTIVE statistics
Subjects
Details
- Language :
- English
- ISSN :
- 00071145
- Volume :
- 109
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- British Journal of Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 87389662
- Full Text :
- https://doi.org/10.1017/S000711451200462X