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Discovering medical conditions associated with periodontitis using linked electronic health records.
- Source :
- Journal of Clinical Periodontology; May2013, Vol. 40 Issue 5, p474-482, 9p, 1 Diagram, 4 Charts, 1 Graph
- Publication Year :
- 2013
-
Abstract
- Aim To use linked electronic medical and dental records to discover associations between periodontitis and medical conditions independent of a priori hypotheses. Materials and Methods This case-control study included 2475 patients who underwent dental treatment at the College of Dental Medicine at Columbia University and medical treatment at NewYork-Presbyterian Hospital. Our cases are patients who received periodontal treatment and our controls are patients who received dental maintenance but no periodontal treatment. Chi-square analysis was performed for medical treatment codes and logistic regression was used to adjust for confounders. Results Our method replicated several important periodontitis associations in a largely Hispanic population, including diabetes mellitus type I ( OR = 1.6, 95% CI 1.30-1.99, p < 0.001) and type II ( OR = 1.4, 95% CI 1.22-1.67, p < 0.001), hypertension ( OR = 1.2, 95% CI 1.10-1.37, p < 0.001), hypercholesterolaemia ( OR = 1.2, 95% CI 1.07-1.38, p = 0.004), hyperlipidaemia ( OR = 1.2, 95% CI 1.06-1.43, p = 0.008) and conditions pertaining to pregnancy and childbirth ( OR = 2.9, 95% CI: 1.32-7.21, p = 0.014). We also found a previously unreported association with benign prostatic hyperplasia ( OR = 1.5, 95% CI 1.05-2.10, p = 0.026) after adjusting for age, gender, ethnicity, hypertension, diabetes, obesity, lipid and circulatory system conditions, alcohol and tobacco abuse. Conclusions This study contributes a high-throughput method for associating periodontitis with systemic diseases using linked electronic records. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03036979
- Volume :
- 40
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Journal of Clinical Periodontology
- Publication Type :
- Academic Journal
- Accession number :
- 86691270
- Full Text :
- https://doi.org/10.1111/jcpe.12086