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Absence of major defects in non-homologous DNA end joining in human breast cancer cell lines.

Authors :
Merel, Philippe
Prieur, Alexandre
Pfeiffier, Petra
Delattre, Olivier
Source :
Oncogene; 8/15/2002, Vol. 21 Issue 36, p5654, 6p, 3 Black and White Photographs, 3 Graphs
Publication Year :
2002

Abstract

Presents a study that investigated the absence of major defects in non-homologous DNA end joining (NHEJ) in human breast cancer cell lines. Main pathways that exist in eukaryotic cells to repair DNA double-strand breaks; In vitro NHEJ accuracy of repair for the pSP65-BP substrate; Western blot analysis of the cell-free extracts for the major proteins involved in the NHEJ process.

Details

Language :
English
ISSN :
09509232
Volume :
21
Issue :
36
Database :
Complementary Index
Journal :
Oncogene
Publication Type :
Academic Journal
Accession number :
8638677