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Selective, Sensitive, and Rapid Analysis with Lateral-Flow Assays Based on Antibody-Gated Dye-Delivery Systems: The Example of Triacetone Triperoxide.

Authors :
Climent, Estela
Gröninger, Delia
Hecht, Mandy
Walter, M. Astrid
Martínez‐Máñez, Ramón
Weller, Michael G.
Sancenón, Félix
Amorós, Pedro
Rurack, Knut
Source :
Chemistry - A European Journal; Mar2013, Vol. 19 Issue 13, p4117-4122, 6p
Publication Year :
2013

Abstract

Set them free: Brightly fluorescent indicators that are loaded into mesoporous silica nanoparticle carriers, capped with bulky antibodies, are released into the lateral flow of a test strip upon analyte arrival. Integration of the system into a rapid, simple flow test with fluorescence readout is applied for the selective and sensitive determination of the presence of triacetone triperoxide (TATP) as a prototype small‐molecule analyte (see figure). [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09476539
Volume :
19
Issue :
13
Database :
Complementary Index
Journal :
Chemistry - A European Journal
Publication Type :
Academic Journal
Accession number :
86049067
Full Text :
https://doi.org/10.1002/chem.201300031