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Efficient synthesis of arylaldehyde oxime ethers functionalised with 3,4-dihydropyrimidinones and 2,5-quinazolinediones via a one-pot two-step method.

Authors :
Quan, Zheng-Jun
Tang, Xue-Hong
Da, Yu-Xia
Zhang, Zhang
Wang, Xi-Cun
Source :
Journal of Chemical Research; Jan2013, Vol. 37 Issue 1, p30-33, 4p, 2 Diagrams, 2 Charts
Publication Year :
2013

Abstract

New arylahdehyde oxime ethers functionalised with N3-3,4-dihydropyrimidinone and 2,5-quinazolinedione groups were synthesised in moderate to good yields by the reaction of the corresponding 3,4-dihydropyrimidinones and quinazolinediones with paraformaldehyde and arylaldehyde oximes via a one-pot two-step strategy in the presence of chlorotrimethylsilane. The advantages of this method are the simple procedure, the high regioselectivity of the products and the mild reaction conditions. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17475198
Volume :
37
Issue :
1
Database :
Complementary Index
Journal :
Journal of Chemical Research
Publication Type :
Academic Journal
Accession number :
85387273
Full Text :
https://doi.org/10.3184/174751912X13546462577913