Differences and similarities in the evolution of morphologic brain abnormalities between paediatric and adult-onset multiple sclerosis.

The article presents a study which compares the evolution of morphologic brain abnormalities between paediatric (p)and adult-onset multiple sclerosis (aMS). The study the examined the differences and similarities in the evolution of the T2- and T1-lesion load (LL), annualised brain volume change (aBVC), and the black hole ratio (BHR), between 21 pMS and aMS patients. Results showed higher compensatory capacity in pMS than aMS based on the observation of the disease evolution.