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Carboxy-Directed Asymmetric Hydrogenation of 1,1-Diarylethenes and 1,1-Dialkylethenes.

Authors :
Song, Song
Zhu, Shou‐Fei
Yu, Yan‐Bo
Zhou, Qi‐Lin
Source :
Angewandte Chemie International Edition; Jan2013, Vol. 52 Issue 5, p1556-1559, 4p
Publication Year :
2013

Abstract

Carboxy marks the spot: A carboxy‐directed asymmetric hydrogenation of 1,1‐diarylethenes and 1,1‐dialkylethenes with chiral iridium/spiro phosphine–oxazoline catalysts has been developed. A wide range of chiral diarylethanes and chiral γ‐methyl fatty acids were synthesized with excellent enantioselectivity (see scheme). [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14337851
Volume :
52
Issue :
5
Database :
Complementary Index
Journal :
Angewandte Chemie International Edition
Publication Type :
Academic Journal
Accession number :
85029428
Full Text :
https://doi.org/10.1002/anie.201208606