Natural killer cells promote immune tolerance by regulating inflammatory TH17 cells at the human maternal-fetal interface.

Authors :: Binqing Fu
Xianchang Li
Rui Sun
Xianhong Tong
Bin Ling
Zhigang Tian
Haiming Wei
Source :: Proceedings of the National Academy of Sciences of the United States of America; 1/15/2013, Vol. 110 Issue 3, p818-819, 2p
Publication Year :: 2013
Abstract: The article offers the authors' insights on a study which shows that T helper 17 (T<subscript>H</subscript>17) cells exist at the maternal-fetal interface in natural allogenic pregnancies. The authors state that natural killer (NK) cells encourage successful pregnancy and immune tolerance. They cite the accumulation of NK cells as the most significant feature of maternal-fetal interface.

Subjects :: T helper cells
IMMUNOLOGICAL aspects of pregnancy
KILLER cells
IMMUNOLOGICAL tolerance
MATERNAL-fetal exchange

Language :: English
ISSN :: 00278424
Volume :: 110
Issue :: 3
Database :: Complementary Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 85001447
Full Text :: https://doi.org/10.1073/pnas.1206322110

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