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A randomized clinical trial of cognitive behavioral therapy and interpersonal psychotherapy for panic disorder with agoraphobia.
- Source :
- Psychological Medicine; Dec2012, Vol. 42 Issue 12, p2661-2672, 12p
- Publication Year :
- 2012
-
Abstract
- Background. Interpersonal psychotherapy (IPT) seems to be as effective as cognitive behavioral therapy (CBT) in the treatment of major depression. Because the onset of panic attacks is often related to increased interpersonal life stress, IPT has the potential to also treat panic disorder. To date, a preliminary open trial yielded promising results but there have been no randomized controlled trials directly comparing CBT and IPT for panic disorder. Method. This study aimed to directly compare the effects of CBT versus IPT for the treatment of panic disorder with agoraphobia. Ninety-one adult patients with a primary diagnosis of DSM-III or DSM-1V panic disorder with agoraphobia were randomized. Primary outcomes were panic attack frequency and an idiosyncratic behavioral test. Secondary outcomes were panic and agoraphobia severity, panic-related cognitions, interpersonal functioning and general psychopathology. Measures were taken at 0, 3 and 4 months (baseline, end of treatment and follow-up). Results. Intention-to-treat (ITT) analyses on the primary outcomes indicated superior effects for CBT in treating panic disorder with agoraphobia. Per-protocol analyses emphasized the differences between treatments and yielded larger effect sizes. Reductions in the secondary outcomes were equal for both treatments, except for agoraphobic complaints and behavior and the credibility ratings of negative interpretations of bodily sensations, all of which decreased more in CBT. Conclusions. CBT is the preferred treatment for panic disorder with agoraphobia compared to IPT. Mechanisms of change should be investigated further, along with long-term outcomes. [ABSTRACT FROM AUTHOR]
- Subjects :
- AGORAPHOBIA
PANIC disorder treatment
ANALYSIS of covariance
COGNITIVE therapy
INTERPERSONAL relations
LONGITUDINAL method
CLASSIFICATION of mental disorders
PSYCHOLOGICAL tests
PSYCHOTHERAPY
QUESTIONNAIRES
STATISTICAL sampling
SCALES (Weighing instruments)
SOUND recordings
T-test (Statistics)
SAMPLE size (Statistics)
EFFECT sizes (Statistics)
RANDOMIZED controlled trials
VISUAL analog scale
DATA analysis software
STATE-Trait Anxiety Inventory
DIARY (Literary form)
DESCRIPTIVE statistics
THERAPEUTICS
Subjects
Details
- Language :
- English
- ISSN :
- 00332917
- Volume :
- 42
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- Psychological Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 83695816
- Full Text :
- https://doi.org/10.1017/S0033291712000876