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Targeting Metabolomics in Breast Cancer.

Authors :
Oakman, Catherine
Tenori, Leonardo
Cappadona S, Silvia
Luchinat, Claudio
Bertini, Ivano
Leo, Angelo
Source :
Current Breast Cancer Reports; Dec2012, Vol. 4 Issue 4, p249-256, 8p
Publication Year :
2012

Abstract

Metabolomics is a science that provides a dynamic portrait of the metabolic status of a biological system. Down from genomics, transcriptomics, and proteomics, metabolomics assesses end product metabolites and small intermediate molecules. In oncology, identification and quantification of metabolites and correlation with critical metabolic pathways in carcinogenesis may provide insight into tumoral biology. In breast cancer, promising early work suggests that metabolomics might enhance current clinical practice by refining biological subclassification, improving prediction of recurrence, and aiding in treatment decisions. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
19434588
Volume :
4
Issue :
4
Database :
Complementary Index
Journal :
Current Breast Cancer Reports
Publication Type :
Academic Journal
Accession number :
83184593
Full Text :
https://doi.org/10.1007/s12609-012-0090-8