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Estimating total body residues and baseline toxicity of complex organic mixtures in effluents and surface waters
- Source :
- Environmental Toxicology & Chemistry; Jul1997, Vol. 16 Issue 7, p1358, 0p
- Publication Year :
- 1997
-
Abstract
- Recently, a new procedure was developed to estimate total body residues (TBRs) in biota after exposure to complex mixtures of organic chemicals in water. The procedure is based on a simulation of bioconcentration using a hydrophobic phase and on the measurement of total molar concentrations on this hydrophobic phase via vapor pressure osmometry and gas chromatography-mass spectrometry. In this paper, the results of the application of this procedure to effluents and surface water are presented. Estimated TBRs (TBR<subscript>est</subscript>s) give informationon the potential total bioaccumulation of complex mixtures. Moreover, using these estimated total body burdens, baseline toxicity effectscan be predicted, including the contributions of chemicals with specific modes of action to the overall baseline toxicity. The advantage of the parameter TBR<subscript>est</subscript> is that it determines total molar concentrations of organic chemicals, including those chemicals that are usually not measured because they cannot be identified or because their concentrations are below the detection limits of individual compounds. [ABSTRACT FROM AUTHOR]
- Subjects :
- BIOACCUMULATION
ENVIRONMENTAL chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 07307268
- Volume :
- 16
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Environmental Toxicology & Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 8283970