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Is the association of breastfeeding with child obesity explained by infant weight change?
- Source :
- International Journal of Pediatric Obesity; Apr2011, Vol. 6 Issue 2Part2, pe415-e422, 8p, 4 Charts, 1 Graph
- Publication Year :
- 2011
-
Abstract
- Objective. Breastfeeding and infant weight change are both associated with adiposity. We examined the extent to which infant weight change mediates the association between breastfeeding and adiposity at age 3 years. Methods. We studied 884 children in a prospective cohort study. We determined breastfeeding status in the first 6 months. Our primary outcomes at 3 years were body mass index (BMI) z score and the sum of subscapular and triceps skinfold thicknesses (SS + TR); we also assessed obesity. We defined infant weight change as change in weight-for-age z score between birth and 6 months. We performed multivariable regression analyses. Results. At age 6 months, 25.0% of infants were fully breastfed. At age 3 years, mean (standard deviation) BMI z score was 0.45 (1.03). In linear regression analyses adjusted for mother's educational level, race/ethnicity, smoking, BMI, pregnancy weight gain and birth weight (adjusted for gestational age), the BMI z score of fully breastfed children was 0.17 (95% CI: −0.43, 0.09) units lower than never breastfed children. After additional adjustment for infant weight change, the estimate was attenuated (−0.03, 95% CI: −0.27, 0.20). Adjustment for infant weight change only modestly attenuated estimates for SS + TR (from −1.48 mm [95% CI: −2.52, −0.44] to −1.16 mm [95% CI: −2.18, −0.14]), and for the odds of being obese (from 0.21 [95% CI: 0.07, 0.68] to 0.29 [95% CI: 0.08, 1.05]). Conclusion. Infant weight change between birth and 6 months mediates associations of breastfeeding with BMI, but only partially with indicators of child adiposity. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17477166
- Volume :
- 6
- Issue :
- 2Part2
- Database :
- Complementary Index
- Journal :
- International Journal of Pediatric Obesity
- Publication Type :
- Academic Journal
- Accession number :
- 79311862
- Full Text :
- https://doi.org/10.3109/17477166.2010.524700