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Matrikines : une nouvelle stratégie thérapeutique anti-cancéreuse.

Authors :
Monboisse, Jean Claude
Sénéchal, Karine
Thevenard, Jessica
Ramont, Laurent
Brassart-Pasco, Sylvie
Source :
Biologie Aujourd'hui; 2012, Vol. 206 Issue 2, p111-123, 13p
Publication Year :
2012

Abstract

The article offers information on the use of matrikines in new anticancer therapeutic strategy. It informs that matrikines are extracellular matrix-derived peptides which regulate cell activity and capable to control tumor invasion and metastasis dissemination. It has been found that during hypoxia proteases secreted by the stromal cells degrade the stromal extracellular matrix which further releases various matrikines.

Details

Language :
French
ISSN :
21050678
Volume :
206
Issue :
2
Database :
Complementary Index
Journal :
Biologie Aujourd'hui
Publication Type :
Academic Journal
Accession number :
78945193
Full Text :
https://doi.org/10.1051/jbio/2012017