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Two new compounds from the fruits of Buddleja lindleyana with neuroprotective effect.
- Source :
- Journal of Asian Natural Products Research; Apr2012, Vol. 14 Issue 4, p342-347, 6p, 2 Diagrams, 2 Charts
- Publication Year :
- 2012
-
Abstract
- Two new triterpenoid glycosides, mimengosides H (1) and I (2), were isolated from the fruits of Buddleja lindleyana Fort. Their structures were determined by extensive spectroscopic methods. Neuroprotective effects of these isolates against 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in PC12 cells were evaluated. Pretreatment with compound 1 had potential protective effect in a concentration range from 0.1 to 1 μmol l− 1. [ABSTRACT FROM PUBLISHER]
- Subjects :
- ANIMAL experimentation
ANTI-infective agents
ANTIFUNGAL agents
CELL surface antigens
CELLS
CHROMATOGRAPHIC analysis
FRUIT
HERBAL medicine
IMMUNODIAGNOSIS
CHINESE medicine
MOLECULAR structure
PARASYMPATHOLYTIC agents
RATS
RESEARCH funding
ROTATIONAL motion
SPECTROPHOTOMETRY
PHYTOCHEMICALS
ENDOCRINE system
ANTIPROTOZOAL agents
NEUROPROTECTIVE agents
DESCRIPTIVE statistics
Subjects
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 14
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 78222917
- Full Text :
- https://doi.org/10.1080/10286020.2011.653783