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Recurrent Acute Pericarditis Induced by 5-aminosalicylates in a Patient with Inflammatory Bowel Disease.
- Source :
- Intestinal Research; 2012, Vol. 10 Issue 3, p289-294, 6p
- Publication Year :
- 2012
-
Abstract
- Inflammatory bowel disease (IBD) is an idiopathic chronic inflammation of the intestines. IBD treatment may require anti-inflammatory agents such as sulfasalazine or 5-aminosalicylate (5-ASA) and immunomodulators to control the symptoms. However, these agents have a variety of common adverse effects such as nausea, vomiting, skin rash, leukopenia, thrombocytopenia, and infections. Moreover, rare side effects such as nephrotic syndrome, pneumonitis, and pericarditis can occur. A 21-year-old male was admitted to the hospital due to acute chest pain, fever, and sweating. The patient had a history of Crohn's disease and had been taking mesalazine for 3 weeks. Chest x-ray, echocardiography, and clinical manifestations revealed that the patient had acute pericarditis. However, we did not recognize the relationship between these findings and 5-ASA at that time. Two years later, the patient took 5-ASA again, and similar symptoms occurred, which led us to confirm that he suffered from pericarditis induced by this drug. We report a case of acute recurrent pericarditis that developed after taking 5-ASA for IBD treatment with a review of the literature. [ABSTRACT FROM AUTHOR]
Details
- Language :
- Chinese
- ISSN :
- 15989100
- Volume :
- 10
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Intestinal Research
- Publication Type :
- Academic Journal
- Accession number :
- 78186162
- Full Text :
- https://doi.org/10.5217/ir.2012.10.3.289