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Mesenchymal and stemness circulating tumor cells in early breast cancer diagnosis.

Source :
BMC Cancer; 2012, Vol. 12 Issue 1, p114-120, 7p, 1 Chart
Publication Year :
2012

Abstract

The article presents the findings of a research conducted on examining circulating tumor cells endowed with mesenchymal or stemness characteristics, at the time of initial diagnosis. It mentions that epithelial mesenchymal transition (EMT) is a crucial event involved in dissemination of epithelial cancer cells. It discusses the methodology of the research. It concludes that mesenchymal or stemness characteristics might facilitate assessment of new drugs in clinical trials.

Details

Language :
English
ISSN :
14712407
Volume :
12
Issue :
1
Database :
Complementary Index
Journal :
BMC Cancer
Publication Type :
Academic Journal
Accession number :
77667540
Full Text :
https://doi.org/10.1186/1471-2407-12-114