Coeliac disease: changing diagnostic criteria?

The author highlights Coeliac Disease (CD), a chronic, multisystemic, autoimmune disorder, induced by gluten exposure in genetically sensitive individuals. He mentions the importance to underline that intestinal biopsy by itself is not always diagnostic and may present many pitfalls. He concludes the current knowledge and complex clinical problems it is evident that the final CD diagnosis is the decision made by the clinician.