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Aberrant hypomethylation of DDX43 promoter in myelodysplastic syndrome.

Authors :
Chen, Qin
Lin, Jiang
Yao, Dong-ming
Qian, Jun
Qian, Wei
Yang, Jing
Chai, Hai-yan
Ma, Ji-chun
Deng, Zhao-qun
Wang, Cui-zhu
Li, Yun
Source :
British Journal of Haematology; Jul2012, Vol. 158 Issue 2, p293-296, 4p, 1 Chart, 1 Graph
Publication Year :
2012

Abstract

The article presents information on effect of abnormal hypomethylation of DDX43, a cancer/testing gene, enhances myelodysplastic syndrome (MDS). It mentions that patients with DDX43 methylation and patients without DDX43 methylation differed only in their clinical characteristic of hemoglobin level. A table depicting DDX43 hypomethylation in MDS patient and two graphs depicting survival of MDS patient are presented.

Details

Language :
English
ISSN :
00071048
Volume :
158
Issue :
2
Database :
Complementary Index
Journal :
British Journal of Haematology
Publication Type :
Academic Journal
Accession number :
77496910
Full Text :
https://doi.org/10.1111/j.1365-2141.2012.09138.x