Chitinase 3-like 1 plasma levels are increased in patients with progressive forms of multiple sclerosis.

Authors :: Cantó, E
Reverter, F
Morcillo-Suárez, C
Matesanz, F
Fernández, O
Izquierdo, G
Vandenbroeck, K
Rodríguez-Antigüedad, A
Urcelay, E
Arroyo, R
Otaegui, D
Olascoaga, J
Saiz, A
Navarro, A
Sanchez, A
Domínguez, C
Caminero, A
Horga, A
Tintoré, M
Montalban, X
Source :: Multiple Sclerosis Journal; Jul2012, Vol. 18 Issue 7, p983-990, 8p, 3 Charts, 3 Graphs
Publication Year :: 2012
Abstract: The article presents a study which examines the role of plasma chitinase 3-like 1 (CHI3LI) in patients with multiple sclerosis (MS) clinican course and the activity of disease. The study used enzyme-linked immunosorbent assay (ELISA) to determine the levels of plasma CHI3L1. Results showed that plasma CHI3L1 levels were importantly increased in patients with progressive for of MS compared with relapsing-remitting (RRMS) patients.

Subjects :: CHITINASE
GLYCOSIDASES
BLOOD plasma
MULTIPLE sclerosis
ENZYME-linked immunosorbent assay
PATIENTS

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