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Hydrophobically Assisted Separation-Friendly Mitsunobu Reaction.

Authors :
Jian Guo
Yu-Jiao Lu
Li Zhang
Xin-Shan Ye
Source :
Synlett; Jul2012, Vol. 23, p1696-1700, 5p
Publication Year :
2012

Abstract

A separation-friendly Mitsunobu reaction using hydrophobic-tagged acids is reported. Commercially available or simply prepared and recyclable hydrophobic-tagged acids can react with various alcohols to afford the target products in high yield with easy purification based on C-18 silica solid-phase extraction or normal silica gel filtration. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09365214
Volume :
23
Database :
Complementary Index
Journal :
Synlett
Publication Type :
Academic Journal
Accession number :
77367678
Full Text :
https://doi.org/10.1055/s-0031-1290406