Glomerulonephropathy in Aged Captive Key Largo Woodrats (Neotoma floridana smalli).

The article describes the pathologic features of a chronic renal disease in aged Key Largo woodrat (KLWR), Neotoma floridana smalli, which are similar to the features of chronic progressive nephropathy (CPN) of laboratory rats. An examination of the kidneys of the woodrats was conducted through light microscopy, histochemical staining and other techniques. It has found that the development and progression of CPN in woodrats was exacerbated by the ad libitum high-protein diet fed to them.