3-D Mouse Brain Model Reconstruction from a Sequence of 2-D Slices in Application to Allen Brain Atlas.

Authors :: Osokin, Anton
Vetrov, Dmitry
Kropotov, Dmitry
Source :: Computational Intelligence Methods for Bioinformatics & Biostatistics: 6th International Meeting, Cibb 2009, Genoa, Italy, October 15-17, 2009, Revised Selected Papers; 2010, p291-303, 13p
Publication Year :: 2010
Abstract: The paper describes a method of fully automatic 3D-reconstruction of a mouse brain from a sequence of histological coronal 2D slices. The model is constructed via non-linear transformations between the neighboring slices and further morphing. We also use rigid-body transforms in the preprocessing stage to align the slices. Afterwards, the obtained 3D-model is used to generate virtual 2D-images of the brain in arbitrary section-plane. We use this approach to construct a high-resolution anatomic 3D-model of a mouse brain using well-known Allen Brain Atlas which is publicly available. [ABSTRACT FROM AUTHOR]

Language :: English
ISBNs :: 9783642145704
Database :: Complementary Index
Journal :: Computational Intelligence Methods for Bioinformatics & Biostatistics: 6th International Meeting, Cibb 2009, Genoa, Italy, October 15-17, 2009, Revised Selected Papers
Publication Type :: Book
Accession number :: 76850671
Full Text :: https://doi.org/10.1007/978-3-642-14571-1_22

Full Text Access

Tools