A region-based palliative care intervention trial using the mixed-method approach: Japan OPTIM study.

The article presents a mixed-method regional intervention trial, consisting of a pre-post outcome study and qualitative process studies. The study is aimed at evaluating the change in the number of home deaths, use of specialized palliative care services, and patient-reported quality of palliative care. It explores the changes in a variety of outcomes including patients' quality of life, pain intensity, and family care burden.