Back to Search
Start Over
Coffee consumption and risk of chronic disease in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Germany study.
- Source :
- American Journal of Clinical Nutrition; Apr2012, Vol. 95 Issue 4, p901-908, 8p
- Publication Year :
- 2012
-
Abstract
- Background: Early studies suggested that coffee consumption may increase the risk of chronic disease. Objective: We investigated prospectively the association between coffee consumption and the risk of chronic diseases, including type 2 diabetes (T2D), myocardial infarction (MI), stroke, and cancer. Design: We used data from 42,659 participants in the European Pro-spective Investigation into Cancer and Nutrition (EPIC)-GenTiany study. Coffee consumption was assessed by self-administered food-frequency questionnaire at baseline, and data on medically verified incident chronic diseases were collected by active and passive follow-up procedures. HRs and 95% CIs were calculated with multivariate Cox regression models and compared by competing risk analysis. Results: During 8.9 y of follow-up, we observed 1432 cases of T2D, 394 of MI, 310 of stroke, and 1801 of cancer as first qualify-ing events. Caffeinated (HR: 0.94; 95% CI: 0.84, 1.05) or decaf-feinated (HR: 1.05; 95% CI: 0.84, 1.31) coffee consumption (>4 cups/d compared with < 1 cup/d; 1 cup was defined as 150 mL) was not associated with the overall risk of chronic disease. A lower risk of T2D was associated with caffeinated (HR: 0.77; 95% CI: 0.63, 0.94; P-trend 0.009) and decaffeinated (HR: 0.70; 95% CI: 0.46, 1.06; P-trend: 0.043) coffee consumption (>4 cups/d compared with < 1 cup/d), but cardiovascular disease and cancer risk were not. The competing risk analysis showed no significant differences between the risk associations of individual diseases. Conclusion: Our findings suggest that coffee consumption does not increase the risk of chronic disease, but it may be linked to a lower risk of T2D. [ABSTRACT FROM AUTHOR]
- Subjects :
- CHRONIC disease risk factors
MYOCARDIAL infarction risk factors
TYPE 2 diabetes risk factors
SMOKING
TUMOR risk factors
STROKE risk factors
COFFEE
CONFIDENCE intervals
DIET
ALCOHOL drinking
EPIDEMIOLOGY
HEALTH behavior
LONGITUDINAL method
MEDICAL cooperation
NUTRITIONAL assessment
RESEARCH
RESEARCH funding
SELF-evaluation
STATISTICAL hypothesis testing
DATA analysis
BODY mass index
PROPORTIONAL hazards models
DATA analysis software
DESCRIPTIVE statistics
Subjects
Details
- Language :
- English
- ISSN :
- 00029165
- Volume :
- 95
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- American Journal of Clinical Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 74582298
- Full Text :
- https://doi.org/10.3945/ajcn.111.023648