Lack of effect of extracorporeal membrane oxygenation on tigecycline pharmacokinetics.

The article discusses the case of a young adult patient who was diagnosed with acute respiratory failure due to intra-alveolar haemorrhage. The patient's treatment regimen include intravenous vancomycin and veno-venous extracorporeal membrane oxygenation (ECMO). A persistent Staphylococcus epidermidis pulmonary infection was seen in the patient. It notes the continued deterioration of the patient's condition and subsequently died in spite of therapy and complete bacteria eradication.