The effect of combination treatment with aliskiren and blockers of the renin-angiotensin system on hyperkalaemia and acute kidney injury: systematic review and meta-analysis.

The article focuses on the systematic review and meta-analysis of the effect of the combination therapy of aliskiren and angiotensin converting enzyme (ACE) inhibitors on the risk of hyperkalaemia and acute kidney injury. It says that the study includes all randomised controlled trials involving aliskiren with ACE inhibitors. It mentions that the results showed that combined used of aliskiren and ACE inhibitors or angiostensin receptor blockers can increase the risk of hyperkalaemia.